CoQ10 and Statin Related Muscle Pain
Efficacy and Safety of COQ10 For Statin-Related Muscle Pain
Polio survivors often ask about muscle pain that can occur with statins and if there is a treatment. "A 2019 randomized controlled trial investigated the effect of CoQ10 on statin-related muscle pain. The study involved 60 participants who had previously reported muscle pain while taking statins. Over 3 months, each participant received daily doses of either 100mg of CoQ10 supplement or a placebo. The participants who took the CoQ10 supplements had significantly reduced statin-related muscle pain. Those who received the placebo reported no change in muscle pain.
However, the authors of a 2015 meta-analysis evaluated the efficacy of CoQ10 supplementation for treating statin-related muscle pain. The meta-analysis included six studies with a combined total of 302 patients. The authors found no evidence that CoQ10 significantly improves statin-related muscle pain." Source Article
"Coenzyme Q10 is LIKELY SAFE for most adults. While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can cause allergic skin rashes in some people. People with chronic diseases such as heart failure, kidney or liver problems, or diabetes should be wary of using this supplement. CoQ10 may lower blood sugar levels and blood pressure. Doses of more than 300 milligrams may affect liver enzyme levels." Source Article
Always have blood drawn for creatine kinase (CK) before starting a statin and if you have muscle pain. And always talk to your doctor before starting anything you buy over the counter.