Medications For Muscle Weakness

Question: My physician has recommended mestinon (Pyridostigmine) for my muscle weakness. Does it help?

Dr. Bruno’s Response: There have been a number of limited quality studies of pyridostigmine's effect on North American and European polio survivors.

The title of this 2003 study says it all: “Pyridostigmine in Post-Polio Syndrome: No decline in fatigue and limited functional improvement.” There wasn’t a decrease in fatigue nor any significant increase in muscle strength for people who took the drug.

Richard L. Bruno, HD, PhD

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October 2022 Newsletter

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“Minor Illnesses” Being Misdiagnosed as Polio