An Old Virus Taking on a New Battle
Dr. Bruno’s Original Post:
This article from Duke Health is fascinating.
HOW THE POLIOVIRUS KILLS CANCER WITH A DOUBLE PUNCH.
". . . poliovirus starts by attaching to malignant cells, which have an abundance of. . .the poliovirus receptor. The modified virus then begins to attack the tumor cells, directly killing many, but not all. By killing the cancer cells, the modified poliovirus triggers an alarm within the immune system, alerting the body’s defenses to go on the attack."
“Not only is poliovirus killing tumor cells, it is also infecting the antigen-presenting cells, which allows them to function in such a way that they can now raise a T-cell response that can recognize and infiltrate a tumor,” Nair said. “This is an encouraging finding, because it means the poliovirus stimulates an innate inflammatory response.” Source: The Full Article